Chidamide Suppresses the Growth of Cholangiocarcinoma by Inhibiting HDAC3 and Promoting FOXO1 Acetylation

Figure 7

Schematic diagram of the mechanism by which CDM affects CCA. CDM inhibits expression of HDAC3 and thus promotes FOXO1 acetylation level, thereby inhibiting the proliferation, migration, and invasion of CCA cells, promoting cell apoptosis and autophagy, and ultimately arresting the growth of CCA.