[Retracted] Extracellular Vesicles Derived from Lung Cancer Cells Induce Transformation of Normal Fibroblasts into Lung Cancer-Associated Fibroblasts and Promote Metastasis of Lung Cancer by Delivering lncRNA HOTAIR

Figure 5

Inhibition of HOTAIR partially reversed the promotion of H358-EVs-mediated CAFs activation on invasion and migration of LC cells. A549 cells were cultured in NFCM treated with H358-EVs-si-HOTAIR for 24 hours. (a) Cell viability was detected by MTT; (b) cell proliferation was detected by CCK-8; (c, d) transwell assay was used to detect cell invasion and migration; (e) cell migration was detected by scratch test. Cell experiment was repeated three times. Repeated measures ANOVA was used for data comparison between groups in Figure (b), and -test was used for data comparison between groups in Figures (a), (c), (d), and (e). .

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