[Retracted] Extracellular Vesicles Derived from Lung Cancer Cells Induce Transformation of Normal Fibroblasts into Lung Cancer-Associated Fibroblasts and Promote Metastasis of Lung Cancer by Delivering lncRNA HOTAIR

Figure 6

T-EVs promoted metastasis of LC in vivo by activating CAFs. A549 cells () of each group were injected into nude mice via the tail vein. After 8 weeks, (a) The lung tissue was weighted, ; (b) the number of tumor nodules was counted, ; (c) HE staining was used to detect tumor foci in lung tissue, ; (d) Ki-67-positive cells were detected by immunohistochemistry, ; and (e) RT-qPCR was used to detect HOTAIR levels in lung tissues, . One-way ANOVA was used for data comparison among multiple groups, and Tukey’s test was used for the post hoc test. .

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