Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes

<div>Macrophages with different polarization phenotypes influenced cementoblast mineralization in the transwell coculture system. (a) Diagram of the transwell coculture system of cementoblasts and M0 and M1- and M2-polarized macrophages. (b) The mRNA expression levels of BSP, COL-1, RUNX2, OSX, and PTPLA in cementoblasts after a 3-day coculture with M0, M1, or M2 (referred to as M0-trans, M1-trans, and M2-trans). (c) Representative chemiluminescent images of BSP, COL-1, RUNX2, and OSX western blots from cementoblasts after a 3-day coculture with M0, M1, or M2 (referred to as M0-trans, M1-trans, and M2-trans). (d) Western blot analysis of BSP, COL-1, RUNX2, and OSX. 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Stem Cells International

fig2

Figure 2

Figure 2: Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes 