Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes

Figure 6

Root resorption, M1/M2 accumulation, and cementoblast mineralization in the mechanical force-induced OTM model. (a) Representative images of HE staining in the roots of the maxillary first molar on the control side and in the short-term OTM (1 d) and long-term OTM (7 d) groups. Black arrows indicate the root resorption zone. Scale bars: 100 μm/50 μm. (b, c) Representative immunohistochemical images of iNOS and PPARγ in the compression side and the tension side of right maxillary first molar roots in the short-term OTM (1 d) and long-term OTM (7 d) groups. Scale bars: 100 μm/50 μm. (d) Representative immunohistochemical images of OSX on the compression side and the tension side of right maxillary first molar roots in the short-term OTM (1 d) and long-term OTM (7 d) groups. Scale bars: 100 μm/50 μm.

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