Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/<i>β</i>-Catenin Pathway

<div>hADSC-Exo promoted the retention and neovascularization of adipose grafts in the nude mice fat grafting model. (a) HE staining revealed that the transplanted fat in the hADSC-Exo groups showed higher adipose number and more complete adipose morphological structure compared to the HFF-Exo group. (b) Semiquantitative scale of integrity of HE staining. (c–f) The number of CD31-positive blood vessels and Ki67-positive proliferating cells in the hADSC-Exo group were significantly higher than that in the HFF-Exo group (<span class="nowrap"><svg height="11.7782pt" id="M16" style="vertical-align:-3.42938pt" version="1.1" viewbox="-0.0498162 -8.34882 52.1858 11.7782" width="52.1858pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M471 153C471 170 463 194 452 212C400 220 373 229 322 255C373 281 400 290 452 298C463 316 471 339 471 357C456 366 431 371 410 370C377 329 356 310 308 279C311 336 317 364 336 413C326 432 310 451 294 459C279 451 262 432 252 413C271 364 277 336 280 279C232 310 211 329 178 370C157 371 132 367 117 357C117 340 125 316 136 298C188 290 215 281 266 255C215 229 188 220 136 212C125 194 117 171 117 153C132 144 157 139 178 140C211 181 232 200 280 231C277 174 271 146 252 97C262 78 278 59 294 51C309 59 326 78 336 97C317 146 311 174 308 231C356 200 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Stem Cells International

fig3

Figure 3

Figure 3: Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/<i>β</i>-Catenin Pathway 

Stem Cells International

Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/β-Catenin Pathway

Figure 3