Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/<i>β</i>-Catenin Pathway

<div>Comprehensive functional analysis of the key DEGs for lipogenesis targeted by hADSC-Exo. (a) The immunofluorescence staining revealed that hADSC-Exo group had evidently significant PPAR<i>γ</i> expression compared to the HFF-Exo group. (b) The positive percentage of PPAR<i>γ</i> expression in the fat grafts at 1, 2, and 3 months were calculated. (c) Volcano plot of the GSE61302 microarray dataset. (d) Venn diagram of key genes which may target by hADSC-Exo in the process of adipogenic differentiation of ADSC. (e) The mapped network for the top 20 hub genes in protein–protein interaction network. (f) The category of “biological process” of the target DEGs. (g) The category of “cellular component” of the target DEGs. 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Stem Cells International

fig5

Figure 5

Figure 5: Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/<i>β</i>-Catenin Pathway 

Stem Cells International

Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/β-Catenin Pathway

Figure 5