Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/β-Catenin Pathway

Figure 6

hADSC-Exo promoted adipogenic differentiation of ADSC in adipose grafts. (a) The category of “KEGG enrichment” of the target DEGs. (B) Clusters of pathways each one presented by a different color. The black lines are the connections between nodes that form the identified lusters, while the red ones are those excluded by the algorithm. (c) Cell adipogenic differentiation assays showed that hADSC-Exo significantly promote ADSC adipogenic differentiation. (d, e) The expression levels of β-catenin in fat grafts cotransplanted with hADSC-Exo or HFF-Exo. (f) A schematic diagram shows how hADSC-Exo promotes the angiogenesis of fat grafts and maintains the adipogenic differentiation ability of ADSC to promote the retention of fat grafts.

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