Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway

Figure 4

Aloin treatment ameliorates the levels of oxidative stress and proinflammatory factors. (a) The mRNA expression levels of NOX1, NOX2, SOD1, and Catalase were detected by qPCR. (b) Protein expression levels of NOX1, NOX2, SOD1, and Catalase were detected by western blotting. (c) The mRNA expression levels of iNOS, COX2, IL-β, and IL-6 were detected by qPCR. (d) Protein expression levels of iNOS and COX2 were detected by western blotting. In this figure, aloin was used at the concentration of 200 μM, while TNF-α was at the concentration of 10 ng/ml. , .

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