Effectiveness and Mechanisms of Low-Intensity Pulsed Ultrasound on Osseointegration of Dental Implants and Biological Functions of Bone Marrow Mesenchymal Stem Cells

<div>LIPUS enhanced the osseointegration of dental implant in <i>α</i>CGRP<sup>+/+</sup> mice. (a) Tooth extraction and implant placement procedure. The red circles indicate bilateral maxillary first molars. The yellow arrow points to the palatal root socket after tooth extraction. (b) Three-dimensional reconstruction of the implant by microcomputed tomography (micro-CT). 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(c) Micro-CT analysis of BIC, BV/TV, Tb.N, and Tb.Sp. 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KO: <i>α</i>CGRP knockout mice; WT: wild type; BIC: bone–implant contact; BV/TV: bone volume/tissue volume fraction; Tb.N: mean trabecular number; Tb.Sp: mean trabecular separation. Reprinted from Jiang et al. [<a href="/journals/sci/2022/7397335/#B24">24</a>], Copyright (2020), with permission from Elsevier.</div>

Stem Cells International

fig1

Figure 1

Figure 1: Effectiveness and Mechanisms of Low-Intensity Pulsed Ultrasound on Osseointegration of Dental Implants and Biological Functions of Bone Marrow Mesenchymal Stem Cells 

Figure 1 | Effectiveness and Mechanisms of Low-Intensity Pulsed Ultrasound on Osseointegration of Dental Implants and Biological Functions of Bone Marrow Mesenchymal Stem Cells 