Long Noncoding RNA Mediated Regulation in Human Embryogenesis, Pluripotency, and Reproduction

Figure 3

Mechanisms of lncRNAs in pluripotency, differentiation, and reprogramming of PSCs by interacting with different partners. Epigenetic regulator: recruit chromatin modification factors to affect chromatin status; transcription factor: binding transcription factors to regulate gene transcriptional activity; RNA-binding protein: interacting with RNA-binding protein to directly regulate protein activity; sponge for miRNA: functioning as the sponge of endogenous miRNA, preventing miRNA targets from degradation.

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