Review Article

Dental Pulp Stem Cell Heterogeneity: Finding Superior Quality “Needles” in a Dental Pulpal “Haystack” for Regenerative Medicine-Based Applications

Table 2

Summary of the marker genes identified to exhibit upregulated expression by microarray analysis, which distinguishes between high proliferative/multipotent hDPSCs and low proliferative hDPSC subpopulations. Adapted from Menicanin et al. [117].

Gene functionsGene symbol

Cell cycle, mitosis, and cell divisionASPM, AURKB, CCNB2, CDC2, CDC20, CENPF, CEP55, CIT, CKS2, DLG7, MAD2L1, NCAPG, PBK, PTTG1, UBE2C
DNA repair and replicationCHEK1, E2F2, GINS2, POLQ, PTTG1, RPA3, RRM2, TOP2A
Transcription regulationCENPF, E2F2, LDB2, PTTG1, TWIST-1
Cell proliferation and differentiationCENPF, CHEK1, CIT, CKS2, TWIST-1