Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment

<div>PDLSCs reduced proliferation and upregulated apoptosis under inflammatory microenvironment. (a) Cell viability of TNF-<i>α</i> treatment groups. (b) mRNA expression levels of Bax/Bcl2 ratio compared to <i>β</i>-actin through qPCR. (c) Protein expression levels of Bax/Bcl2 ratio compared to <i>β</i>-actin through western blot. (d) Cell apoptosis rate of TNF-<i>α</i> treatment groups. 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Stem Cells International

fig2

Figure 2

Figure 2: Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 

Figure 2 | Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 