Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment

<div>EPO rescued inflammation and apoptosis levels of PDLSCs under inflammatory microenvironment. (a) Cell viability of EPO treatment groups. (b) mRNA expression levels of IL-1<i>β</i> and IL-8 compared to <i>β</i>-actin through qPCR. (c, d) mRNA and protein expression levels of Bax/Bcl2 ratio compared to <i>β</i>-actin through qPCR and western blot. (e) Cell apoptosis rate of EPO treatment groups. 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Stem Cells International

fig4

Figure 4

Figure 4: Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 

Figure 4 | Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 