Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment

<div>EPO promoted autophagy and angiogenesis of PDLSCs under inflammatory microenvironment. (a, b) mRNA and protein expression levels of VEGF-a, FGF-2, and IGF-1 compared to <i>β</i>-actin through qPCR and western blot. (c) Tube formation under EPO treatment. (d, e) mRNA and protein expression levels of Beclin1 and LC3B compared to <i>β</i>-actin through qPCR and western blot. 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Stem Cells International

fig5

Figure 5

Figure 5: Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 

Figure 5 | Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 