Bone Marrow-Derived Mesenchymal Stem Cells and γ-Secretase Inhibitor Treatments Suppress Amyloid-β25–35-Induced Cognitive Impairment in Rat Dams and Cortical Degeneration in Offspring

Figure 7

Effect of treatment with MSCs and GSI-953 on (a) number of degenerated neural cells/mm, (b) outer molecular layer thickness (μm) in the newborn cortex of Aβ25–35-induced Alzheimer’s disease dams. Data were analyzed via two-way ANOVA followed by Tukey’s multiple comparison test. Data are expressed as . , , and vs. the saline-injected group. ^#, ^##, and ^### vs. the AD group. ^ns no significant.

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