Photobiomodulation Can Enhance Stem Cell Viability in Cochlea with Auditory Neuropathy but Does Not Restore Hearing

Figure 9

Lack of teratoma formation in extensively proliferated ES cells transplanted into the cochlea after secondary neurodegeneration. Teratoma formation of survived GFP-mESCs in the deformed cochlea after 2 weeks of combination therapy. SOX1, a marker for neuroectoderm formation, was investigated in SC-treated cochleae. SOX1 was not expressed in tested groups including the survived GFP-positive cells of the cochlea. It can be suggested the mESCs did not promote teratoma formation. Scale bar = 50 µM.