Exosomal miR-141-3p from PDLSCs Alleviates High Glucose-Induced Senescence of PDLSCs by Activating the KEAP1-NRF2 Signaling Pathway

Figure 9

Schematic of the rejuvenating effects of exosomes produced by PDLSCs. High glucose levels accelerated cellular senescence in PDLSCs. PDLSC-Exos protected against high glucose-induced PDLSC senescence by transferring miR-141-3p to senescent PDLSCs to decrease KEAP1 expression and activate the NRF2 antioxidant pathway. (This image was created using Figdraw).