Melatonin Promotes BMSCs Osteoblastic Differentiation and Relieves Inflammation by Suppressing the NF-κB Pathways

Figure 3

Melatonin inhibited inflammatory response in BMSCs. (a–c) RT-PCR was used to detect the expression of proinflammatory genes, such as IL-1β, IL-6, and TNF-α in BMSCs. (d) RT-PCR was used to detect anti-inflammatory IL-10 gene expression in BMSCs. MT-50: 50 μM melatonin; MT-100: 100 μM melatonin. Data are expressed as the from three independent experiments. versus control (Con) group.

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