Immunization with Embryonic Stem Cells/Induced Pluripotent Stem Cells Induces Effective Immunity against Ovarian Tumor-Initiating Cells in Mice

Table 1

In vivo tumorigenicity of sorted ID8 spheroid cells in NOD/SCID mice.

Number of inoculated cells	Rate of tumor formation
	CD133^+	(%)	CD133^−	(%)	P-value (Fisher’s exact test, Two-sided)
100	5/5	100	0/5	0	0.0079
500	5/5	100	0/5	0	0.0079
2,000	5/5	100	3/5	60	0.4444
10,000	5/5	100	5/5	100	>0.9999

Twenty NOD/SCID female mice were randomly divided into four groups. Various numbers (100, 500, 2,000, and 10,000) of viable CD133-positive and CD133-negative cells in PBS/Matrigel (1 : 1) were subcutaneously injected into the right and left flanks of NOD/SCID mice separately. The rate of tumor formation refers to the number of tumors formed/number of inoculated mice.