Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans

Figure 2

Associated APC subpopulations in adipose tissue of different anatomical origin. (a. Single-cell atlas showing APC subpopulations. (b) Single-cell atlas showing APC subpopulations in abdominal subcutaneous adipose tissue-leg adipose tissue-visceral adipose tissue. (c) Differential abundance of APC subpopulations in abdominal subcutaneous adipose tissue-leg adipose tissue-visceral adipose tissue. (d) Series of single-cell atlases showing markers for specific cell subpopulations. (e) Biological processes are significantly activated by APC subpopulations. (f) Signaling pathways are significantly activated by APC subpopulations. (g) Pseudotime analysis demonstrating pseudotime values (left) and pseudotime trajectories (middle), and cell stemness (right) of APC subpopulations. (h) Coexpression modules of transcription factors in APC. Identification of regulator modules based on the connection specificity index (CSI) matrix of regulators (left). Representative transcription factors and their binding patterns in the modules (middle:). Cell subpopulations where transcription factors are located (right). (i) Transcription factors that have regulatory effects on APC subpopulations.

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