Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans

Figure 5

Subpopulations of associated hASCs cells in adipose tissue of different anatomical origins. (a) Single-cell atlas showing hASCs subpopulations. (b) Single-cell atlas showing hASCs subpopulations in abdominal subcutaneous adipose tissue-leg adipose tissue-visceral adipose tissue. (c) Differential abundance of hASCs subpopulations in abdominal subcutaneous adipose tissue-leg adipose tissue-visceral adipose tissue. (d) Series of single-cell atlases showing markers for specific cell subpopulations. (e) Biological processes are significantly activated by hASCs subpopulations. (f) Signaling pathways are significantly activated by hASCs subpopulations. (g) Pseudotime analysis demonstrating pseudotime values (left), pseudotime trajectories (middle), and cell stemness (right) of hASCs subpopulations. (h) Coexpression modules of transcription factors in hASCs. Identification of regulator modules based on the connection specificity index (CSI) matrix of regulators (left). Representative transcription factors and their binding patterns in the modules (middle). cell subpopulations where transcription factors are located (right). (i) Transcription factors that have regulatory effects on hASCs subpopulations.

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