Mesenchymal Stem Cells Accelerate Recovery of Acetic Acid-Induced Chronic Gastric Ulcer by Regulating Ekt/Akt/TRIM29 Axis

Figure 2

The hUC-MSCs promotes acetic acid-induced gastric ulcers healing in mice: (a) macroscopic observation of gastric ulcers, both serous membrane and gastric mucosa on Day 5 in the groups of Sham, Model, MSC, and MSC-CM; (b) the quantitative results of ulcer area in the gastric serosal and mucosal layers; (c) food take on the Day 4 (the day before the mice were sacrificed), the weight of gastric contents on the Day 5, and the increasing rate of body weight; (d) microscopic images (40×, 200×) of H&E staining of gastric tissues in each group; (e) ulcer area, the length of the ruptured muscularis mucosae and the thickness of the ulcer base of gastric tissues were measured based on H&E staining scanning results. Neutrophils infiltration, lymphocytes infiltration, and mucosal edema of gastric tissues were assessed (n = 10) (indicate , indicate .).

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