Role of Angiogenesis and Its Biomarkers in Development of Targeted Tumor Therapies

Figure 1

Diagrammatic presentation of vasculogenesis and angiogenesis, where hemangioblastic aggregates are formed from undifferentiated mesoderm, which further proceeds to endothelial precursor cells (packed in blood island) and primitive erythrocytes packed in layers of ECs. Also, tip cells sprout out of the proliferating and migrating ECs to form capillary tube [9].