Stem Cells International

Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical Applications


Status
Published

1Kazan Federal University, Kazan, Russia

2Lund University, Malmö, Sweden

3Yeditepe Üniversitesi, Istanbul, Turkey

4Justus Liebig University, Giessen, Germany

5University of Coimbra, Cantanhede, Portugal


Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical Applications

Description

Despite advances in biomedical and clinical research, many diseases and conditions have no known cure or still do not have adequate therapies which would result in sufficient recovery and high quality of life of patients. Boosting natural regenerative abilities of human body seems to be a promising therapeutic strategy. Stem cells possess an ability to self-renew and differentiate into several cell types, thus playing an important role in natural replacement of aged or apoptotic cells and regeneration of damaged tissues. Mesenchymal and hematopoietic stem cells play an important role in many regeneration processes in human body. Moreover, according to recent studies, mesenchymal and hematopoietic stem cells form a unique bone marrow niche. Not surprisingly, hematopoietic and mesenchymal stem cells are considered the most promising adult stem cell types for developing cell and gene-cell based therapies.

We elicit reviews, original papers, and clinical studies focused on using hematopoietic and mesenchymal stem cells in fundamental biomedical and clinical application.

Potential topics include, but are not limited to:

  • Using hematopoietic and mesenchymal stem cells in regenerative medicine for treating neurodegenerative diseases (Alzheimer’s disease, amyotrophic lateral sclerosis, multiple sclerosis, Parkinson’s disease, etc.), ischemic diseases (brain ischemia, limb ischemia, myocardial infraction, etc.), various traumas (peripheral nerve injury, spinal cord injury, bone and ligament fractures, burns, etc.), organ and tissue failure (liver, kidney, lung, etc.), and others
  • Hematopoietic and mesenchymal stem cells in tissue engineering (3D printing, decellularized tissues and organs, natural and artificial matrixes, etc.)
  • Immunomodulatory effects of mesenchymal stem cells and participation of mesenchymal stem cells in establishing hematopoietic microenvironment and promoting engraftment of hematopoietic stem cells during bone marrow and umbilical cord blood transplantation
  • Novel isolation, culture/expansion, and differentiation procedures for hematopoietic and mesenchymal stem cells
  • Using genetic modification and chemical treatments for modulating biological properties of hematopoietic and mesenchymal stem cells

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 3157365
  • - Editorial

Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical Applications

Albert A. Rizvanov | Jenny Persson | ... | Paulo J. Oliveira
  • Special Issue
  • - Volume 2016
  • - Article ID 4612167
  • - Review Article

Mesenchymal Stem Cells as a Prospective Therapy for the Diabetic Foot

Qinan Wu | Bing Chen | Ziwen Liang
  • Special Issue
  • - Volume 2016
  • - Article ID 1247950
  • - Research Article

Modulation of Synovial Fluid-Derived Mesenchymal Stem Cells by Intra-Articular and Intraosseous Platelet Rich Plasma Administration

Emma Muiños-López | Diego Delgado | ... | Mikel Sánchez
  • Special Issue
  • - Volume 2016
  • - Article ID 7152761
  • - Research Article

Magnet-Bead Based MicroRNA Delivery System to Modify CD133+ Stem Cells

Paula Müller | Natalia Voronina | ... | Robert David
  • Special Issue
  • - Volume 2016
  • - Article ID 9434250
  • - Review Article

Modulation of Immunoregulatory Properties of Mesenchymal Stromal Cells by Toll-Like Receptors: Potential Applications on GVHD

Bruno Sangiorgi | Rodrigo Alexandre Panepucci
  • Special Issue
  • - Volume 2016
  • - Article ID 4798639
  • - Review Article

Mesenchymal Stem Cell-Based Therapy for Kidney Disease: A Review of Clinical Evidence

Anna Julie Peired | Alessandro Sisti | Paola Romagnani
  • Special Issue
  • - Volume 2016
  • - Article ID 7174319
  • - Research Article

Infusion of Bone Marrow Mesenchymal Stem Cells Attenuates Experimental Severe Acute Pancreatitis in Rats

Hang Zhao | Zhiying He | ... | Zhaoshen Li
  • Special Issue
  • - Volume 2016
  • - Article ID 9742034
  • - Research Article

Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hindlimb Ischemia through Enhancing Angiogenesis in Tree Shrews

Cunping Yin | Yuan Liang | ... | Xinghua Pan
  • Special Issue
  • - Volume 2016
  • - Article ID 1625015
  • - Review Article

Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models

Pallavi Sontakke | Jenny Jaques | ... | Jan Jacob Schuringa
  • Special Issue
  • - Volume 2016
  • - Article ID 2892840
  • - Review Article

Mesenchymal Stem Cells and Metabolic Syndrome: Current Understanding and Potential Clinical Implications

Kenichi Matsushita
Stem Cells International
 Journal metrics
Acceptance rate44%
Submission to final decision76 days
Acceptance to publication35 days
CiteScore7.200
Impact Factor3.869
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