TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets

<table>A schematic diagram to illustrate the diverse roles of TRPM7 and TRPM8 channels as potential clinical biomarkers and therapeutic targets in pancreatic adenocarcinoma, and also as growth and migratory regulators in normal exocrine pancreas and in malignant neoplasia of pancreas.  The various roles of TRPM7 and TRPM8 are likely applicable to other malignant tumors that exhibit aberrant expression and/or activities of TRPM7 and TRPM8.</table>

Scientifica

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Figure 5

Figure 5: TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets 