Review Article
Plasma Membrane Transporters in Modern Liver Pharmacology
Table 1
Identified potential substrates of hepatic forms of OATPs with pharmacological interest.
| | OATP1B1 | OATP1B3 | OATP1A2 |
| Substrates | Benzylpenicillin | | | Bile acid derivatives (BAMETS) | Bile acid derivatives (BAMETS) | Bile acid derivatives (BAMETS) | Bilirubin and its conjugates | Bilirubin conjugates | | Bosentan | Bosentan | | BQ-123 | BQ-123 | BQ-123 | Bromosulfophthalein | Bromosulfophthalein | Bromosulfophthalein | Caspofungin | | | Cerivastatin | Cholecystokinin-8 | | Cholic acid | | Cholic acid | DHEA sulphate | DHEA sulphate | DHEA sulphate | | Deltorphin II | Deltophorin II | | Digoxin | | DPDPE | DPDPE | DPDPE | | Docetaxel | | Enalapril | Enalapril | | Estradiol 17β-glucuronide | Estradiol 17β-glucuronide | | Estrone-3-sulphate | | Estrone-3-sulphate | | Fexofenadine | Fexofenadine | Flavopiridol | Flavopiridol | | Fluvastatin | Fluvastatin | | Glycocholate | Glycocholate | Glycocholate | Irinotecan and SN-38 | Irinotecan and SN-38 | | | | Imatinib | | | Levofloxacin | Leukotriene C4 | Leukotriene C4 | | Methotrexate | Methotrexate | Methotrexate | Microcystin-LR | Microcystin-LR | Microcystin-LR | Olmesartan | Olmesartan | | | Ouabain | Ouabain | Paclitaxel | Paclitaxel | | Phalloidin | Phalloidin | | | | D-Penicillamine | Pravastatin | | Pravastatin | Prostaglandin E2 | | Prostaglandin E2 | Rifampicin | Rifampicin | | Rosuvastatin | Rosuvastatin | Rosuvastatin | | | Saquinavir | Taurocholate | Taurocholate | Taurocholate | | Telmisartan | | Thromboxane B2 | | | Thyroxine | Thyroxine | Thyroxine | Triiodothyronine | Triiodothyronine | Triiodothyronine | Troglitazone sulphate | | | Valsartan | Valsartan | |
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