Comparative Analysis of the Full-Length Genome Sequence of a Clinical Isolate of Human Parainfluenza Virus 4B
Phylogram depicting the relationship of hPIV-4B isolate 04-13 to representative members of the genus Rubulavirus. Tree based on the concatenated deduced amino acid sequences of the F, H-N, L, M, NP, and P proteins (4442 amino acid characters including gaps). Members of the genus Avulavirus (Newcastle disease virus; NDV and Avian paramyxovirus 6; APMV6) were included as outgroups. All nodes were supported by a posterior probability of 100. Branch lengths are based on the number of inferred substitutions, as indicated by the scale. Gene sequences were obtained from the complete genomic sequences for NDV (RefSeq accession no. NC_002617), APMV6 (NC_003043), Mumps virus (MuV; NC_002200), human parainfluenza virus 2 (HPIV2; NC_003443), Simian virus 41 (SV41; NC_006428), Simian virus 5 (SV5; NC_006430), human parainfluenza virus 4A (HPIV4A; GenBank accession no. AB543336), hPIV-4B (04-13; AB543337, 68–333; JQ241176, SKPIV4; EU627591).