Spontaneous and Procedural Plaque Embolisation in Native Coronary Arteries: Pathophysiology, Diagnosis, and Prevention

Figure 3

Mechanisms leading to left ventricular impairment after distal embolisation. Inflammatory response and shear stress at the interface between embolised and non embolised myocardium trigger the cytokines cascade which leads to myofibrillar proteins oxidation and reduced calcium responsiveness, underlying left ventricular dysfunction after distal embolization.