Review Article

Rhinovirus-Induced Exacerbations of Asthma and COPD

Figure 1

Images of bronchial epithelium from an adult subject without asthma who was experimentally infected with rhinovirus-16. (a) Hematoxylin and eosin stain shows an intact epithelium. (b) Tissue was stained for RV16 capsid protein (red) and DAPI, a nuclear stain. Note that some cells are stained with RV and others are not. (c) Tissue was stained with mouse IgG, a negative control, and DAPI. Note the absence of red staining. Antibody against RV16 and tissue blocks were generously provided by Wai-Ming Lee, Nizar Jarjour, and Jim Gern (University of Wisconsin).
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