Biogenesis and Biological Activity of Secondary siRNAs in Plants
Complex network regulation of siTAARs initiated by miR393. Upon cleavage of TIR1/AFB2 auxin receptor (TAAR) transcripts by miR393 (red lines), secondary siRNAs (siTAARs) are generated. siTAARs regulate the expression of their source transcript in cis (dark lines) of other TAAR transcripts in trans (transverse dark lines) and of unrelated transcripts (blue lines) in trans. The network has important role in auxin homeostasis and plant development.