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Volume 2014, Article ID 278039, 10 pages
Review Article

A New Approach in Risk Stratification by Coronary CT Angiography

Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, CA 90502, USA

Received 24 April 2014; Accepted 15 August 2014; Published 1 September 2014

Academic Editor: Albert V. Bruschke

Copyright © 2014 Rine Nakanishi and Matthew J. Budoff. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks. CCTA can provide more information incorporating the presence, extent, and severity of CAD; coronary plaque burden; and characteristics that highly correlate with those on invasive coronary angiography. Moreover, recent techniques of CCTA allow assessing hemodynamic significance of CAD. CCTA may be potentially used as a substitute for other invasive or noninvasive modalities. This review summarizes risk stratification by anatomical and hemodynamic information of CAD, coronary plaque characteristics, and burden observed on CCTA.