Computational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of β-Secretase

Figure 6

Most favorable binding modes of the ligands L1–L8 ((a) to (h), resp.) obtained from the docking procedure.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)