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Scientifica
Volume 2014 (2014), Article ID 726179, 6 pages
http://dx.doi.org/10.1155/2014/726179
Research Article

Detection of β-Lactamases and Outer Membrane Porins among Klebsiella pneumoniae Strains Isolated in Iran

1Department of Microbiology, Shahid Beheshti University of Medical Sciences, P.O. Box 19857-17443, Tehran, Iran
2Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Received 16 March 2014; Revised 18 July 2014; Accepted 18 July 2014; Published 3 August 2014

Academic Editor: Maurizio Sanguinetti

Copyright © 2014 Ali Hashemi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. Pitart, M. Solé, I. Roca, A. Fàbrega, J. Vila, and F. Marco, “First outbreak of a plasmid-mediated carbapenem-hydrolyzing OXA-48 β-lactamase in Klebsiella pneumoniae in Spain,” Antimicrobial Agents and Chemotherapy, vol. 55, no. 9, pp. 4398–4401, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. Y. Pfeifer, K. Schlatterer, E. Engelmann et al., “Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals,” Antimicrobial Agents and Chemotherapy, vol. 56, no. 4, pp. 2125–2128, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. G. Cuzon, J. Ouanich, R. Gondret, T. Naas, and P. Nordmann, “Outbreak of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in France,” Antimicrobial Agents and Chemotherapy, vol. 55, no. 5, pp. 2420–2423, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. L. Poirel, T. R. Walsh, V. Cuvillier, and P. Nordmann, “Multiplex PCR for detection of acquired carbapenemase genes,” Diagnostic Microbiology and Infectious Disease, vol. 70, no. 1, pp. 119–123, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Rastegar Lari, L. Azimi, M. Rahbar, F. Fallah, and R. Alaghehbandan, “Phenotypic detection of Klebsiella pneumoniae carbapenemase among burns patients: first report from Iran,” Burns, vol. 39, no. 1, pp. 174–176, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Chen, F. Hu, X. Xu et al., “High prevalence of KPC-2-type carbapenemase coupled with CTX-M-type extended-spectrum β-lactamases in carbapenem-resistant Klebsiella pneumoniae in a teaching hospital in China,” Antimicrobial Agents and Chemotherapy, vol. 55, no. 5, pp. 2493–2494, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. Y. K. Tsai, C. P. Fung, J. C. Lin et al., “Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence,” Antimicrobial Agents and Chemotherapy, vol. 55, no. 4, pp. 1485–1493, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. CaLS Institute, Performance Standards for Antimicrobial Susceptibility Testing, 22nd information supplement (M 100-S22), Clinical and Laboratory Standards Institute, Wayne, Pa, USA, 2012.
  9. I. Galani, P. D. Rekatsina, D. Hatzaki, D. Plachouras, M. Souli, and H. Giamarellou, “Evaluation of different laboratory tests for the detection of metallo-β-lactamase production in Enterobacteriaceae,” The Journal of Antimicrobial Chemotherapy, vol. 61, no. 3, pp. 548–553, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. F. D. Halstead, G. L. Vanstone, and I. Balakrishnan, “An evaluation of the mast D69C AmpC detection disc set for the detection of inducible and derepressed AmpC β-lactamases,” Journal of Antimicrobial Chemotherapy, vol. 67, no. 9, Article ID dks170, pp. 2303–2304, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. D. Landman, S. Bratu, and J. Quale, “Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae,” Journal of Medical Microbiology, vol. 58, no. 10, pp. 1303–1308, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. I. Pakzad, M. Zayyen Karin, M. Taherikalani, M. Boustanshenas, and A. R. Lari, “Contribution of AcrAB efflux pump to ciprofloxacin resistance in Klebsiella pneumoniae isolated from burn patients,” GMS Hygiene and Infection Control, vol. 8, no. 2, 2013. View at Google Scholar
  13. A. Taherpour and A. Hashemi, “Detection of OqxAB efflux pumps, OmpK35 and OmpK36 porins in extended-spectrum-β-lactamase-producing Klebsiella pneumoniae isolates from Iran,” Hippokratia, vol. 17, no. 4, pp. 355–358, 2013. View at Google Scholar
  14. F. Fallah, A. Taherpour, R. S. Borhan, A. Hashemi, M. Habibi, and R. Sajadi Nia, “Evaluation of Zataria MultiFlora Boiss and Carum copticum antibacterial activity on IMP-type metallo-β-lactamase-producing Pseudomonas aeruginosa,” Annals of Burns and Fire Disaster, vol. 26, no. 4, pp. 193–198, 2013. View at Google Scholar
  15. S. Ghafourian, Z. B. Sekawi, N. Sadeghifard et al., “The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran,” The Open Microbiology Journal, vol. 5, pp. 91–95, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. M. M. Feizabadi, S. Mohammadi-Yeganeh, A. Mirsalehian et al., “Genetic characterization of ESBL-producing strains of Klebsiella pneumoniae from Tehran hospitals,” Journal of Infection in Developing Countries, vol. 4, no. 10, pp. 609–615, 2010. View at Google Scholar · View at Scopus
  17. M. Ahangarzadeh Rezaee, N. Langarizadeh, and M. Aghazadeh, “First report of class 1 and class 2 integrons in multidrug-resistant Klebsiella pneumoniae isolates from northwest Iran,” Japanese Journal of Infectious Diseases, vol. 65, no. 3, pp. 256–259, 2012. View at Google Scholar
  18. C. R. de Alegria, J. Rodriguez-Bano, M. E. Cano et al., “Klebsiella pneumoniae strains producing extended-spectrum β-lactamases in Spain: microbiological and clinical features,” Journal of Clinical Microbiology, vol. 49, no. 3, pp. 1134–1136, 2011. View at Publisher · View at Google Scholar
  19. A. R. Lari, L. Azimi, M. Rahbar, R. Alaghehbandan, and M. Sattarzadeh-Tabrizi, “First report of Klebsiella pneumonia carbapenemase-producing Pseudomonas aeruginosa isolated from burn patients in Iran: phenotypic and genotypic methods,” GMS Hygiene and Infection Control, vol. 9, no. 1, 2014. View at Publisher · View at Google Scholar
  20. F. Shahcheraghi, S. Nobari, F. Rahmati Ghezelgeh et al., “First report of new delhi metallo-β-lactamase-1-producing Klebsiella pneumoniae in Iran,” Microbial Drug Resistance, vol. 19, no. 1, pp. 30–36, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Rodríguez-Baño, E. Miró, M. Villar et al., “Colonisation and infection due to Enterobacteriaceae producing plasmid-mediated AmpC β-lactamases,” Journal of Infection, vol. 64, no. 2, pp. 176–183, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. Y. T. Thean, L. S. Y. Ng, J. He, H. K. Tse, and Y. H. Li, “Evaluation of screening methods to detect plasmid-mediated AmpC in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis,” Antimicrobial Agents and Chemotherapy, vol. 53, no. 1, pp. 146–149, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Shin, D. H. Kim, and K. S. Ko, “Comparison of CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae isolates from patients with bacteremia,” Journal of Infection, vol. 63, no. 1, pp. 39–47, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. M. M. Feizabadi, S. Delfani, N. Raji et al., “Distribution of blaTEM, blaSHV, blaCTX-M genes among clinical isolates of Klebsiella pneumoniae at Labbafinejad Hospital, Tehran, Iran,” Microbial Drug Resistance, vol. 16, no. 1, pp. 49–53, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. H. Goudarzi, S. Aghamohammad, A. Hashemi, B. Nikmanesh, and M. Noori, “Distribution of blaTEM, blaSHV and blaCTX-M genes among Escherichia coli isolates causing urinary tract infection in children,” in Archives of Clinical Infectious Diseases, vol. 8, 3 edition, 2013. View at Google Scholar
  26. A. Potron, P. Nordmann, E. Rondinaud, F. Jaureguy, and L. Poirel, “A mosaic transposon encoding OXA-48 and CTX-M-15: towards pan-resistance,” Journal of Antimicrobial Chemotherapy, vol. 68, no. 2, pp. 476–477, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. L. Garcia-Sureda, C. Juan, A. Domenech-Sanchez, and S. Alberti, “Role of Klebsiella pneumoniae LamB Porin in antimicrobial resistance,” Antimicrobial Agents and Chemotherapy, vol. 55, no. 4, pp. 1803–1805, 2011. View at Google Scholar