Perfluorocarbon Nanoparticles: Evolution of a Multimodality and Multifunctional Imaging Agent

Figure 2

PARACEST nanoparticles display a very obvious saturation transfer effect at 52 ppm (arrow), resulting from saturation of the bound water peak which is effectively transferred into the bulk water pool. Nanoparticles that do not contain the PARACEST chelate do not show any saturation transfer effects at this frequency offset. Reprinted with permission from [56].