Influenza Viral Manipulation of Sphingolipid Metabolism and Signaling to Modulate Host Defense System
Interaction between SK1 and viruses. (a) SK1 inhibits BVDV replication, whereas SK1 heightens cellular susceptibility to the infection with influenza virus or HCMV. (b) BVDV and DENV decrease SK1 expression/activation, whereas influenza virus, HCMV, and RSV increase SK1 level/activation.
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