Review Article
CYP2A6 Polymorphisms May Strengthen Individualized Treatment for Nicotine Dependence
Figure 1
Factors influencing nicotine behavior and metabolism rate. Note. Environmental, cultural, and social factors may influence the development of nicotine intake, but nicotine metabolism is best modulated by CYP2A6 genes which release cotinine into blood to reach brain inducing pleasurable feeling for smokers.