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Scientifica
Volume 2015, Article ID 613089, 6 pages
http://dx.doi.org/10.1155/2015/613089
Research Article

Clinical Outcomes from Unselected “Real-World” Patients with Long Coronary Lesion Receiving 40 mm Biodegradable Polymer Coated Sirolimus-Eluting Stent

1Lalitha Super Specialty Hospital Pvt. Ltd., Heart and Brain Centre, Kothapet, Guntur, Andhra Pradesh 522001, India
2Apollo Hospitals, Ahmedabad, Gujarat 382428, India
3Lions Sterling Super Specialty Hospital, Mehsana, Gujarat 384002, India
4Yashfeen Cardiac Hospital, Navsari, Gujarat 396445, India
5Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat, Gujarat 395004, India

Received 29 June 2015; Revised 3 October 2015; Accepted 8 October 2015

Academic Editor: Costantino Del Gaudio

Copyright © 2015 Anurag Polavarapu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Long lesions being implanted with drug-eluting stents (DES) are associated with relatively high restenosis rates and higher incidences of adverse events. Objectives. We aimed to examine the safety and efficacy of the long (40 mm) biodegradable polymer coated Indolimus sirolimus-eluting stent (SES) in real-world patients with long coronary lesions. Methods. This study was observational, nonrandomized, retrospective, and carried out in real-world patients. A total of 258 patients were enrolled for the treatment of long coronary lesions, with 40 mm Indolimus. The primary endpoints in the study were incidence of major adverse cardiac events (MACE), a miscellany of cardiac death, myocardial infarction (MI), target lesion revascularization (TLR) or target vessel revascularization (TVR), and stent thrombosis (ST) up to 6-month follow-up. Results. The study population included higher proportion of males (74.4%) and average age was 53.2 ± 11.0 years. A total of 278 lesions were intervened successfully with 280 stents. The observed MACE at 6-month follow-up was 2.0%, which included 0.8% cardiac death and 1.2% MI. There were no TLR or TVR and ST observed during 6-month follow-up. Conclusions. The long (40 mm) Indolimus stent demonstrated low MACE rate and was proven to be safe and effective treatment for long lesions in “real-world” patients.