Review Article

Onychomycosis: Potential of Nail Lacquers in Transungual Delivery of Antifungals

Table 5

Patent reports on nail lacquer for transungual drug delivery.

Patent/application number (year of issue/publication)Original assignee/applicantCommentReference

CA2400178 A1 (2001) Gyurik RJ, Bentley Pharmaceuticals, Inc., Exeter, New Hampshire, USA; Cpex Pharmaceuticals, Inc., Wilmington, Delaware, USADepicting an innovation based on a pharmaceutical composition containing a permeation enhancer that enhances the rate of passage of a pharmaceutical compound across the nail or membrane[32]
US6254878 B1 (2001)E.I. Du Pont De Nemours & Company, Wilmington, Delaware, USAInventing acrylic based nail polish and its composition containing binders and dispersants or both[33]
US6391879 B1 (2001)Astan, Inc., Birmingham, Alabama, USADisclosing a therapy and its application in the treatment of nail fungal infection (onychomycosis) composed of an antifungal drug with DMSO in polyglycolic solution[34]
US6495124B1 (2002)Macrochem Corporation, Wellesley, MassachusettsDescribing nail lacquer for fungal infections containing drugs like econazole/ciclopirox in a polymeric film of pentadecalactone/lactone and a solvent (volatile)[35]
US6622064 B2 (2003)Imx Labs, Inc., Birmingham, Oakland, MichiganDisclosing a nail polish color. Its methods and dispensing have been described[36]
US8771655 B2 (2014)Debra MarinoRevealing a naturally developed nail polish prepared with fruits/vegetables containing acrylic polymer[37]
US20120178056A1 (2012)Cindy NelsonDisclosing a colored and translucent nail polish prepared with different colors[38]
US20130149266 A1 (2013)Michael Mitsuo Homma, Victor Masaru HommaProviding long residing and easily dried nail polish comprising a lacquer and pigment composition[39]
US20150190331 A1 (2015)Pakaly Enterprise Co., Ltd., Chung-Ho, Taipei, TaiwanInventing a gel based polish comprising (meth)acrylate monomer like ethyl methacrylate and hydroxyethylmethacrylate [40]
WO2003007675 A2 (2003)Benny Borsakian, Janel FaraciDisclosing a nail polish preparation containing a base, colorant, and a photochromic powder[41]