Research Article

Histomorphological and Immunohistochemical Reappraisal of Cutaneous Adnexal Tumours: A Hospital Based Study

Table 9

Salient histopathological feature of troublesome tumours.

Sweat gland tumour (digital papillary tumour)(i) Multinodular epithelial aggregates with cystic spaces in the dermis.
(ii) Papillary epithelial projections within cystic spaces associated with fibrovascular cores in some areas.
(iii) The epithelium made of low columnar cells and cysts filled with eosinophilic material.
(iv) Mitoses and necrosis seen.

Hidradenoma papilliferum(i) Dermal nodule with scattered cystic and branching spaces.
(ii) Numerous papillary projections lined by single layer of high cylindric cells with a basal layer.
(iii) Active decapitation secretions.

Chondroid syringoma(i) Nodular tumour.
(ii) Branching tubular epithelial cells in basophilic stroma.
(iii) Tubular lumina lined by cuboidal cells (luminal) and flat cells (periphery).
(iv) Mucoid stroma.

Trichilemmal carcinoma(i) Invasive tumour with solid and trabecular pattern seen.
(ii) Cytologically atypical clear cells with foci of pilar type keratinization.

Desmoplastic trichoepithelioma(i) Narrow strands of tumour cells
(ii) Numerous horn cysts
(iii) Desmoplastic stroma
(iv) Areas of calcification