Research Article
A FACS Based Case Study on Two HbE-β Thalassaemia Members of a Family, Having Similar Mutational Background
Table 1
Clinical data of the members of the family in study.
| | Clinical parameters | P1 (father) | P2 (mother) | P3 (elder brother) | P4 (younger brother) |
| | Haemoglobin (g/dL) | 6.8 | 11.2 | 11.4 | 4.1 | | MCV (fL) | 48.5 | 54.2 | 50.3 | 57.0 | | MCH (pg) | 17.2 | 21.1 | 21.2 | 16.6 | | MCHC (%) | 35.4 | 38.9 | 42.2 | 29.2 | | Rdw (%) | 29.0 | 23.6 | 22.2 | 26.4 | | Hct (%) | 19.3 | 26.8 | 27.1 | 14.2 | | HbA2/E (%) | 8.1 | 73.6 | 90.3 | 17.8 | | HbA0 (%) | 83.2 | 3.6 | 2.1 | 70.3 | | HbF (%) | 5.3 | 2.1 | 1.7 | 4.0 | | P3 (%) | 3.3 | 5.3 | 5.1 | 4.7 | | History of blood transfusion (BT) | No | No | No | 1st BT on 8 months and then on monthly BT |
|
|
MCV = Mean Cell Volume; MCH = Mean Cell Haemoglobin; MCHC = Mean Cell Haemoglobin Concentration; Rdw = Red Cell Distribution Width; Hct = Haematocrit.
|
