Analysis and Enhancements of a Prolific Macroscopic Model of Epilepsy

Figure 1

Core models. (a) Initial model [10] showing pyramidal (P) and interneuron (I) subgroups with either excitatory or inhibitory projections. is a random input. (b) Extended model [18]. (c) Detailed diagram of computational components for pyramidal cells (solid lines), excitatory interneurons (dotted lines), and inhibitory interneurons (dashed lines). Pulse-to-voltage blocks are labeled “”, and voltage-to-pulse blocks are labeled “”. The IPSP block is distinguished from the EPSP blocks by a waveform showing negative deflection.

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