In Utero Nutritional Manipulation Provokes Dysregulated Adipocytokines Production in F1 Offspring in Rats
Table 1
Hepatic and muscular content of TGs (mg/g tissue) in different study groups.
Age (weeks)
Sex
CF1-CD
CF1-HCD
OF1-CD
OF1-HCD
MF1-CD
MF1-HCD
Hepatic TGs content (mg/g tissue)
5
Male
76 ± 7
79 ± 8
75 ± 7
81 ± 8
74 ± 8
77 ± 8
Female
75 ± 6
76 ± 5
75 ± 6
77 ± 5
71 ± 6#
76 ± 6
10
Male
82 ± 8
84 ± 8
82 ± 7
88 ± 8
79 ± 7
82 ± 9
Female
78 ± 5
81 ± 6
82 ± 7
86 ± 7
75 ± 5
83 ± 8
15
Male
83 ± 7
92 ± 9
86 ± 9
98 ± 10
83 ± 9
85 ± 10
Female
81 ± 5
84 ± 7
85 ± 7
97 ± 6
78 ± 6
88 ± 7
20
Male
86 ± 8
94 ± 8
90 ± 7
105 ± 10
84 ± 8
91 ± 8
Female
82 ± 6
87 ± 6
89 ± 8
102 ± 9
85 ± 7
93 ± 7
25
Male
94 ± 9
98 ± 9
96 ± 8
111 ± 9
91 ± 10
95 ± 7
Female
87 ± 6
94 ± 7
98 ± 9
105 ± 10
88 ± 9
94 ± 8
30
Male
99 ± 8
103 ± 10
111 ± 9
129 ± 11
96 ± 8
102 ± 9
Female
93 ± 7
95 ± 8
106 ± 8
114 ± 11
95 ± 10
104 ± 9
Muscular TGs content (mg/g tissue)
5
Male
1.53 ± 0.12
1.52 ± 0.12
1.54 ± 0.10
1.6 ± 0.21
1.45 ± 0.11
1.5 ± 0.1
Female
1.46 ± 0.12
1.53 ± 0.13
1.51 ± 0.14
1.55 ± 0.17
1.42 ± 0.13
1.48 ± 0.11
10
Male
1.75 ± 0.13
1.94 ± 0.14
1.81 ± 0.13
2.21 ± 0.2
1.6 ± 0.12
1.75 ± 0.15
Female
1.65 ± 0.13
1.81 ± 0.14
1.66 ± 0.12
1.93 ± 0.16
1.64 ± 0.14
1.74 ± 0.13
15
Male
1.79 ± 0.12
2.11 ± 0.12
1.9 ± 0.14
2.5 ± 0.22
1.7 ± 0.16
1.84 ± 0.14
Female
1.71 ± 0.13
1.87 ± 0.13
1.84 ± 0.14
2.28 ± 0.18
1.72 ± 0.17
1.8 ± 0.13
20
Male
2.02 ± 0.11
2.17 ± 0.13
2.1 ± 0.12
2.7 ± 0.23
2 ± 0.18
2.1 ± 0.17
Female
1.88 ± 0.13
1.92 ± 0.14
2.0 ± 0.17
2.43 ± 0.21
1.91 ± 0.14
1.98 ± 0.21
25
Male
2.14 ± 0.13
2.22 ± 0.16
2.3 ± 0.14
2.8 ± 0.21
2 ± 0.12
2.1 ± 0.18
Female
1.97 ± 0.12
2.13 ± 0.12
2.25 ± 0.16
2.5 ± 0.18
1.98 ± 0.19
2.11 ± 0.21
30
Male
1.89 ± 0.14
2.24 ± 0.15
2.3 ± 0.15
3 ± 0.26
2.1 ± 0.16
2.1 ± 0.17
Female
1.84 ± 0.12
1.99 ± 0.13
2.2 ± 0.16
2.68 ± 0.21
2.07 ± 0.17
2.2 ± 0.12
Data are presented as mean ± SD (). CF1-CD: F1 offspring of control mothers under control diet, CF1-HCD: F1 offspring of control mothers under HCD, OF1-CD: F1 offspring of obese mothers under control diet, and OF1-HCD: F1 offspring of obese mothers under HCD, MF1-CD: F1 offspring of malnourished mothers under control diet, and MF1-HCD: F1 offspring of malnourished mothers under HCD. The symbol indicates significant difference from CF1-CD by ANOVA (), the symbol # indicates significant difference from CF-HCD by ANOVA (), and the symbol @ indicates significant difference from male at each age by -test.