Research Article

In Utero Nutritional Manipulation Provokes Dysregulated Adipocytokines Production in F1 Offspring in Rats

Table 1

Hepatic and muscular content of TGs (mg/g tissue) in different study groups.

Age (weeks)SexCF1-CDCF1-HCDOF1-CDOF1-HCDMF1-CDMF1-HCD

Hepatic TGs content (mg/g tissue)
5Male76 ± 779 ± 875 ± 781 ± 874 ± 877 ± 8
Female75 ± 676 ± 575 ± 677 ± 571 ± 6#76 ± 6
10Male82 ± 884 ± 882 ± 788 ± 879 ± 782 ± 9
Female78 ± 581 ± 682 ± 786 ± 775 ± 583 ± 8
15Male83 ± 792 ± 986 ± 998 ± 1083 ± 985 ± 10
Female81 ± 584 ± 785 ± 797 ± 678 ± 688 ± 7
20Male86 ± 894 ± 890 ± 7105 ± 1084 ± 891 ± 8
Female82 ± 687 ± 689 ± 8102 ± 985 ± 793 ± 7
25Male94 ± 998 ± 996 ± 8111 ± 991 ± 1095 ± 7
Female87 ± 694 ± 798 ± 9105 ± 1088 ± 994 ± 8
30Male99 ± 8103 ± 10111 ± 9129 ± 1196 ± 8102 ± 9
Female93 ± 795 ± 8106 ± 8114 ± 1195 ± 10104 ± 9
Muscular TGs content (mg/g tissue)
5Male1.53 ± 0.121.52 ± 0.121.54 ± 0.101.6 ± 0.211.45 ± 0.111.5 ± 0.1
Female1.46 ± 0.121.53 ± 0.131.51 ± 0.141.55 ± 0.171.42 ± 0.131.48 ± 0.11
10Male1.75 ± 0.131.94 ± 0.141.81 ± 0.132.21 ± 0.21.6 ± 0.121.75 ± 0.15
Female1.65 ± 0.131.81 ± 0.141.66 ± 0.121.93 ± 0.161.64 ± 0.141.74 ± 0.13
15Male1.79 ± 0.122.11 ± 0.121.9 ± 0.142.5 ± 0.221.7 ± 0.161.84 ± 0.14
Female1.71 ± 0.131.87 ± 0.131.84 ± 0.142.28 ± 0.181.72 ± 0.171.8 ± 0.13
20Male2.02 ± 0.112.17 ± 0.132.1 ± 0.122.7 ± 0.232 ± 0.182.1 ± 0.17
Female1.88 ± 0.131.92 ± 0.142.0 ± 0.172.43 ± 0.211.91 ± 0.141.98 ± 0.21
25Male2.14 ± 0.132.22 ± 0.162.3 ± 0.142.8 ± 0.212 ± 0.122.1 ± 0.18
Female1.97 ± 0.122.13 ± 0.122.25 ± 0.162.5 ± 0.181.98 ± 0.192.11 ± 0.21
30Male1.89 ± 0.142.24 ± 0.152.3 ± 0.153 ± 0.262.1 ± 0.162.1 ± 0.17
Female1.84 ± 0.121.99 ± 0.132.2 ± 0.162.68 ± 0.212.07 ± 0.172.2 ± 0.12

Data are presented as mean ± SD (). CF1-CD: F1 offspring of control mothers under control diet, CF1-HCD: F1 offspring of control mothers under HCD, OF1-CD: F1 offspring of obese mothers under control diet, and OF1-HCD: F1 offspring of obese mothers under HCD, MF1-CD: F1 offspring of malnourished mothers under control diet, and MF1-HCD: F1 offspring of malnourished mothers under HCD. The symbol indicates significant difference from CF1-CD by ANOVA (), the symbol # indicates significant difference from CF-HCD by ANOVA (), and the symbol @ indicates significant difference from male at each age by -test.