Extract of Sesbania grandiflora Ameliorates Hyperglycemia in High Fat Diet-Streptozotocin Induced Experimental Diabetes Mellitus
Table 1
Effect of MESG on body weight, abdominal girth, and food intake during different days of diet manipulating period and drug treatment period.
Treatment group
Parameters
Different days of diet manipulating period
Different days of drug treatment period
0
14
28
0
14
28
Group I Normal control
Body weight (gm)
151.67 ± 3.00
160.83 ± 2.39
172.50 ± 3.35
178.33 ± 2.47
187.50 ± 2.14
196.67 ± 3.33
Abdominal girth (cm)
13.82 ± 0.15
14.28 ± 0.10
14.73 ± 0.20
14.95 ± 0.21
15.35 ± 0.19
15.73 ± 0.15
Food intake (gm)
15.63 ± 0.47
15.98 ± 0.62
16.45 ± 0.58
16.85 ± 0.88
17.02 ± 0.95
17.18 ± 0.92
Group II Diabetic control
Body weight (gm)
153.33 ± 3.07
182.50 ± 3.10
221.67 ± 3.57
239.17 ± 3.96
224.17 ± 3.00
211.67 ± 2.47
Abdominal girth (cm)
13.52 ± 0.23
15.62 ± 0.32
17.32 ± 0.19
18.17 ± 0.15
18.38 ± 0.19
18.37 ± 0.19
Food intake (gm)
17.03 ± 0.80
14.18 ± 0.62
13.52 ± 1.05
14.43 ± 0.60
18.62 ± 0.65
20.23 ± 0.63
Group III Metformin treated
Body weight (gm)
157.50 ± 3.82
186.67 ± 3.33
225.83 ± 3.33
243.33 ± 3.57
235.83 ± 2.39
231.67 ± 3.33
Abdominal girth (cm)
12.82 ± 0.36
14.98 ± 0.29
16.65 ± 0.22
17.57 ± 0.20
17.08 ± 0.19
16.52 ± 0.25
Food intake (gm)
16.70 ± 0.87
14.03 ± 0.80
13.48 ± 0.92
14.27 ± 0.77
16.90 ± 0.80
17.18 ± 0.98
Group IV 200 mg/kg MESG treated
Body weight (gm)
150.83 ± 3.07
181.67 ± 2.47
216.67 ± 2.47
235.83 ± 2.39
226.17 ± 3.00
230.83 ± 2.39
Abdominal girth (cm)
13.10 ± 0.16
15.32 ± 0.12
17.02 ± 0.12
17.93 ± 0.18
17.58 ± 0.19
17.22 ± 0.18
Food intake (gm)
16.13 ± 0.73
14.48 ± 0.75
12.98 ± 1.08
14.98 ± 1.25
17.05 ± 0.82
17.95 ± 0.98
Group V 400 mg/kg MESG treated
Body weight (gm)
154.17 ± 2.39
187.50 ± 2.81
223.33 ± 3.07
244.17 ± 2.39
236.67 ± 2.47
241.67 ± 2.47
Abdominal girth (cm)
13.93 ± 0.41
15.77 ± 0.15
17.55 ± 0.20
18.43 ± 0.17
17.95 ± 0.19
17.50 ± 0.19
Food intake (gm)
15.78 ± 0.38
13.45 ± 0.62
12.40 ± 0.53
13.78 ± 0.65
16.28 ± 1.12
17.43 ± 0.70
The results were expressed as mean ± SEM, . , , and , diabetic control versus normal control. , , and , metformin treated and MESG treated groups versus diabetic control group. “#” indicates that there is no significant difference between metformin treated and MESG treated groups at .
