Extract of Sesbania grandiflora Ameliorates Hyperglycemia in High Fat Diet-Streptozotocin Induced Experimental Diabetes Mellitus
Table 2
Effect of MESG on blood glucose level and urine analysis during different days of drug treatment period.
Parameters
Different days
Group I Normal control
Group II Diabetic control
Group III Metformin treated
Group IV 200 mg/kg MESG treated
Group V 400 mg/kg MESG treated
Blood glucose
0
84.67 ± 3.52
239.17 ± 6.11
237.50 ± 5.21
244.17 ± 6.64
243.33 ± 4.91
14
81.83 ± 2.95
223.33 ± 5.12
162.83 ± 5.21
201.17 ± 4.53
182.67 ± 4.38
28
83.33 ± 3.15
217.67 ± 5.47
124.33 ± 4.81
166.50 ± 4.32
145.17 ± 4.51
Urine volume (mL)
0
5.48 ± 0.25
8.32 ± 0.18
8.23 ± 0.22
7.68 ± 0.20
7.82 ± 0.19
14
5.57 ± 0.22
8.17 ± 0.20
6.02 ± 0.26
6.67 ± 0.25
6.42 ± 0.25
28
5.28 ± 0.24
8.47 ± 0.21
5.47 ± 0.27
6.05 ± 0.26
5.38 ± 0.29
Presence of glucose in urine
0
14
28
Presence of ketone bodies in urine
0
14
28
The results were expressed as mean ± SEM, . ; diabetic control versus normal control. , , and , metformin treated and MESG treated groups versus diabetic control group. “#” indicates that there is no significant difference between metformin treated and MESG treated groups at . “+” indicates being present and “−” indicates being absent.
