Advances in the Use of Stem Cells in Veterinary Medicine: From Basic Research to Clinical Practice

Figure 1

The influence of MSC on the niche. According to the signaling factors that the MSC are exposed, different decisions may be taken, where the main ones are those that are involved in proliferation and cellular differentiation. The MSC capture and send molecular signals, which change the niche, either by modulating the immune system as providing mechanisms for tissue repair effectors, involving since activation of cell homing, cell apoptosis, induction of the formation of new blood vessels, and the healing process.