Research Article

Calcium Alginate and Calcium Alginate-Chitosan Beads Containing Celecoxib Solubilized in a Self-Emulsifying Phase

Table 1

Composition of calcium alginate and calcium alginate-chitosan beads.

FormulationSodium alginate (% w/w)Self-emulsifying phase (% w/w)Gelling bathNeedle diameter (μm)

Cal 6001.5Celecoxib 27.4CaCl2 100 mM600
Labrasol 68.5
TPGS 4.1

Cal 4001.5Celecoxib 27.4CaCl2 100 mM400
Labrasol 68.5
TPGS 4.1

CAlCh 6001.5Celecoxib 27.4CaCl2 100 mM + 0.2% chitosan600
Labrasol 68.5
TPGS 4.1

CAlCh 4001.5Celecoxib 27.4CaCl2 100 mM + 0.2% chitosan400
Labrasol 68.5
TPGS 4.1