Optimization of Thermoreversible In Situ Nasal Gel of Timolol Maleate

Table 2

Coded level for variable (f1–f9).

Independent variables	Coded levels
	−1	0	+1
HPMC conc. (% w/w)	0.8%	1.2%	1.6%
Poloxamer 407 conc. (% w/w)	46%	50%	54%