Optimization of Thermoreversible In Situ Nasal Gel of Timolol Maleate

Table 7

Comparison of predicted and actual values of % drug release.

Polymers	Coded levels	Actual levels	Response	% drug release	Gelation temperature
			Predicted value	78.38	32.58
			Observed value	93.57	35
HPMC	0	0.8	Standard deviation	2.2213	0.3438
Poloxamer 407	0	46	Standard error mean	2.43	0.38